SKU: 1395

Mobility (60)

Mobility (60)

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Price:$46.50

Anti-Inflammatory*               Natural Pain Relief*


A comprehensive formula consisting of a symphony of powerful herbal extracts designed to reduce pain and inflammation all without causing the numerous side-effects associated with many other pain remedies.

Price:$46.50

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Product Description

 A Natural Solution For Reducing Pain and Inflammation

Humans have been practicing various forms of pain management and taking pain remedies for thousands of years from the pain pipes of Native Americans to modern day pharmaceutical drugs and over the counter (OTC) pain medications. As it has become more increasingly apparent today, many of the drug-derived pain relief remedies come with unwanted side-effects. Educated consumers know to ask the question “What risk am I willing to take on in order to receive the benefit of pain relief?” Recent research published from the most reputable medical journal in England, The Lancet, has found  ibuprofen (brand names: Advil, Motrin), to pose the same cardiovascular risk as Vioxx (Merck ), a drug that was removed from the market for the same such risks1.

A New York Times article in 2012, discussed how Americans consume Ibuprofen with a false sense of security to the point that many athletes (70% of distance runners) consume the drug as a preventative measure for pain. A recent study proved that consuming Ibuprofen before athletic events will actually increase inflammation by causing leakage of protein and enzymes from your intestines into the blood causing systemic inflammation2.

Side effects associated with OTC medications include:3

  • Nausea

  • Heartburn

  • Stomach upset

  • Rash

  • Liver damage

  • Increased risk of heart attack and stroke

A Unique Combination of Inflammation-Pain Reducing Compounds

The Mobility Difference

Aceva’s Mobility  is a comprehensive formula consisting of a symphony of powerful herbal extracts designed to reduce pain and inflammation all without causing the numerous side-effects associated with many other pain remedies.

Turmeric                                 

Turmeric is an orange spice derived from from India that has been used for thousands of years in both cooking and medicine. It’s active constituents called curuminoids have been shown to support cardiovascular function, gastrointestinal (GI) health and enhance cognition. Curcuminoids have also been shown to play a crucial role in maintaining proper inflammatory balance in a variety of bodily systems due to their ability to modulate the inflammatory NF-kB pathway. Many studies have demonstrated the clinical efficacy of the curcuminoids, including their ability help promote GI health by helping balance inflammation in the body,4,5 promoting GI mucosal health and helping to reduce stomach lining discomfort6. The isolated curcuminoid, curcumin, has been shown to reduce oxidative stress, improve intestinal permeability and improve mood and fatigue7 as well as provide antioxidant protection to the cardiovascular system8.

White Willow Bark                        

White Willow Bark (WWB) is an herb well known for its ability to reduce pain and inflammation. It’s earliest recorded dates way back to 500 B.C. by Chinese Physicians. The inner bark of the willow tree contains salicin which converts to salicylic acid in the body, the same compound in Aspirin that is attributed to providing its efficacious benefits. As a result of the diverse blend of antioxidants contained in its bark, WWB has been shown to be an extremely effective analgesic. Herbalists have used WWB to promote health in many ways including to help reduce fevers, pain, inflammation and to help mitigate menstruation symptoms.

Ginger                                        

Ginger is a flowering plant whose therapeutic constituents (gingerols) are derived from its root. Ginger has many different therapeutic and has been used historically to help with arthritis and other inflammatory conditions. Its anti inflammatory effects have been attributed to its ability to inhibit the cyclooxygenase and lipoxygenase pathways in the body9.  One double-blind trial showed that ginger was just effective as anti-inflammatory medication in helping relieve symptoms of dysmenorrhea10. Multiple double blind trials have demonstrated ginger’s ability to improve osteoarthritis symptoms, further demonstrating its powerful anti-inflammatory effects11,12.

Rosemary Leaf

Rosemary has been touted as a polycrest remedy due to its multiple therapeutic benefits. It has a longstanding historical use for aiding in pain management and muscular ailments. It is thought to provide these benefits by helping improve circulation, improve the flow of congested blood and stimulating the nerves which results in the restoration of muscle sensation.

5-loxin ® Indian Frankincense (Boswellia serrata)            

Indian Frankincense (Boswellia serrata) is a branching tree derived from India whose active constituents (boswellic acids) have been traditionally used in the Ayurvedic medicine as an antiarthritic, astringent, stimulant, expectorant, and antiseptic. Boswellic acids are selective 5-lipoxygenase inhibitors, meaning they can strategically help promote a healthy inflammatory balance in the body. 5-loxin ® contains at least 30% AKBA, the most biologically active boswellic acid. A double-blind, placebo-controlled trial showed that 5-loxin ® was able to significantly improve osteoarthritis symptoms13. Seventy patients were split into 3 groups and were evaluated for a 90 day period: 100 mg daily, 250 mg daily and a placebo. Both the 100 mg and 250 mg groups saw significant improvements in pain (100 mg: 54% reduction; 250 mg: 59% reduction), stiffness (100 mg: 56% reduction; 250 mg: 67% reduction)  and improvement in overall function (100 mg: 41% improvement; 250 mg: 55% improvement) as measured by the WOMAC score as well as reduction in the levels of the cartilage degrading enzyme MMP-3 (100 mg: 29% reduction; 250 mg: 46% reduction) in 90 days. The study also showed that subjects receiving the 250 mg daily experienced relief in as little as 7 days, demonstrating the ingredient’s ability to provide immediate relief.

Bioperine® Black Pepper

Black Pepper has been touted as the “King of Spices” throughout the world due to its pungent properties and therapeutic effects. Bioperine® is a patented form of Black Pepper extract  (Piper nigrum) that is sometimes co-administered with other ingredients in order to enhance their bioavailability. In general, the addition of Bioperine® is thought to increase the bioavailability of other nutrients by around 30%14.


Supplemental Facts

Supplemental Facts

SUPPLEMENT FACTS

Serving Size: 1 Capsule

 

Servings per Container: 60

 

 

 

 

AMOUNT PER SERVING
% Daily Value

 

 

 

 

Turmeric Root Extract (standardized to 95% curcuminoids)

300

mg

White Willow Bark Extract (standardized to 15% salicin)

75

mg

Ginger Root Extract (5% gingerols)

50

mg

Rosemary Leaf Extract

50

mg

5-LOXIN®  Indian Frankicense Gum Extract

50

mg

BioPerine®  Black Pepper Fruit Extract (95% Piperine)

5

mg

† Daily Value not established

Other Ingredients: Vegatarian Capsule (hypromellose), Rice Flour, L-Leucine

 

 

 

 

           

Suggested Use

Suggested Use

Suggested Use:

As a dietary supplement, take one (1) capsule two times daily or as directed by your healthcare professional.

Caution:

Do not use this product if you are pregnant or nursing. As with any dietary supplement, consult your healthcare practitioner before using this product, especially if you anticipate surgery, take any medication or are otherwise under medical supervision.

Formulated To Be Free of Allergens Derived From:

Wheat, soy, dairy, eggs, fish, crustacean shellfish, tree nuts, peanuts, artificial preservatives, sweeteners, color and flavors. 


* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FAQs

FAQ's

Research

References and Research Abstracts Supporting Pain-X 

1. The Lancet, Volume 382, Issue 9894, Pages 769 - 779, 31 August 2013. doi:10.1016/S0140-6736(13)60900-9

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6. Lee JH, Kim GH. Evaluation of antioxidant and inhibitory activities for different subclasses flavonoids on enzymes for rheumatoid arthritis. J Food Sci. 2010 Sep;75(7):H212-7. doi: 10.1111/j.1750-3841.2010.01755.x. PubMed PMID: 21535545.

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14. Balasubramanian K. Molecular Orbital Basis for Yellow Curry Spice Curcumin's Prevention of Alzheimer's Disease. J. Agric. Food Chem., 54 (10), 3512 -3520, 2006. 10.1021/jf0603533 S0021-8561(06)00353-0, Web Release Date: April 20, 2006. 2006.

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23. Fiala M, Liu PT, Espinosa-Jeffrey A, Rosenthal MJ, Bernard G, Ringman JM, Sayre J, Zhang L, Zaghi J, Dejbakhsh S, Chiang B, Hui J, Mahanian M, Baghaee A, Hong P, Cashman J. Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12849-54. 2007. PMID:17652175.

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26. Gururaj A, Kelakavadi M, Venkatesh D et al. Molecular mechanisms of anti-angiogenic effect of curcumin. Biochem Biophys Res Commun 2002 Oct 4;297(4):934 2002.

27. Hidaka H, Ishiko T, Furunashi T et al. Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface:impacgt on human pancrreatic carcinoma cell growth by autocrine regulation. Cancer 2002 Sep 15;96(6):1206-14 2002.

28. Kang BY, Chung SW, Chung W et al. Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophage by curcumin. Eur J Pharmacol 1999 Nov;384(2-3):191-5 1999.

29. Kang BY, Song YJ, Kim KM et al. Curcumin inhibits Th1 cytokine profile in CD4+ T cells by suppressing interleukin-12 production in macrophages. Br J Pharmacol 1999 Sep;128(2):380-4 1999.

30. Khor TO, Keum YS, Lin W, Kim JH, Hu1 R, Shen G, Xu1 C, Gopalakrishnan A, Reddy B, Zheng X, Conney AH, Kong AN. Combined Inhibitory Effects of Curcumin and Phenethyl Isothiocyanate on the Growth of Human PC-3 Prostate Xenografts in Immunodeficient Mice. Cancer Research. 2006 Jan; 66(2): 613-621. 2006. PMID:16423986.

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